publications

accelerating research

Featured Publication

July 2019

Branche, E, Simon, AY, Sheets, N, Kim, K, Barker, D, Nguyen, AT, Sahota, H, Young, MP,  Salgado, R, Mamidi, A, Viramontes, KM, Carnelley, T, Qiu, H, Ngono, AE, Regla-Nava, JA, Susantono, MX, Valls Cuevas, JM, Kennedy, K, Kodihalli, S, & Shresta, S

Albers, RE, Kaufman, MR, Natale, BV, Keoni, C, Kulkarni-Datar, K, Min, S, Williams, CR, Natale, DRC & Brown, TL  (2019) Trophoblast-Specific Expression of Hif-1α Results in Preeclampsia-Like Symptoms and Fetal Growth Restriction. Scientific Reports 9, 2742.

Boehme, SA, Franz-Bacon, K, DiTirro, DN, Ly, TW, & Bacon, KB (2016) MAP3K19 Is a Novel Regulator of TGF-β Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis. PLoS ONE 11(5): e0154874.

Boehme, SA, Franz-Bacon, K, Ludka, J, DiTirro, DN, Ly, TW, & Bacon, KB (2016) MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction. PLoS ONE 11(12): e0167169.

Branche, E, Simon, AY, Sheets, N, Kim, K, Barker, D, Nguyen, AT, Sahota, H, Young, MP,  Salgado, R, Mamidi, A, Viramontes, KM, Carnelley, T, Qiu, H, Ngono, AE, Regla-Nava, JA, Susantono, MX, Valls Cuevas, JM, Kennedy, K, Kodihalli, S, & Shresta, S  (2019) Human Polyclonal Antibodies Prevent Lethal Zika Virus Infection in Mice. Scientific Reports 9, 9857.

Butt, NA,  Kumar, A, Dhar, S,  Rimando, AM, Akhta, I, Hancock, JC, Lage, JM,  Pound, CR, Lewin JR, Gomez, CR, & Levenson, AS (2017) Targeting MTA1/HIF‐1α signaling by pterostilbene in combination with histone deacetylase inhibitor attenuates prostate cancer progression. Cancer Medicine 6(11), 2673-2685.

Dhar, S,  Kumar, A, Gomez, CR,  Akhtar, I, Hancock, JC,  Lage, JM, Pound, CR, & Levenson, AS (2017) MTA1‐activated Epi‐microRNA‐22 regulates E‐cadherin and prostate cancer invasiveness. FEBS Letters 591(6), 924-933.

Dillon, GM, Tyler, WA, Omuro, KC, Kambouris, J, Tyminski, C, Henry, S, Haydar, TF, Beffert, U, & Ho, A (2017) CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development. Neuron 93(6), 1344-1358.

Geisz A & Sahin-Tóth, M  (2018) A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation. Nature Communications 9, 5033.

Han, L, Bittner, S, Dong, D, Cortez, Y, Dulay, H, Arshad, S, Shen, W, Kraemer, FB, & Azhar, S (2019) Creosote bush-derived NDGA attenuates molecular and pathological changes in a novel mouse model of non-alcoholic steatohepatitis (NASH). Molecular and Cellular Endocrinology 498. DOI: 10.1016/j.mce.2019.110538.

Hilton, HG, Rubinstein, ND, Janki, P, Ireland, AT, Bernstein, N, Wright, KM, Finkle, D, Martin-McNulty, B, Roy, M, Smith, M, Imai, DM, Jojic, V, & Buffenstein, R (2019) Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity. bioRxiv, Apr. 4, 2019; doi: http://dx.doi.org/10.1101/597195.

Ji, J, Judkowski, VA, Liu, G, Wang, H, Bunying, A., Li, Z, Xu, M, Bender, J, Pinilla, C, & Yu, JS (2014) Identification of Novel Human Leukocyte AntigenA*0201-Restricted, Cytotoxic T Lymphocyte Epitopes on CD133 for Cancer Stem Cell Immunotherapy. Stem Cells Translational Medicine 3, 356–364.

Kianna Y. Elahi-Gedwillo, KY, Marjorie Carlson, M, Jon Zettervall, J, & Provenzano, PP (2019) Antifibrotic Therapy Disrupts Stromal Barriers and Modulates the Immune Landscape in Pancreatic Ductal Adenocarcinoma. Cancer Research 79(2), 372-386.

Lyman, M, Lieuw, V, Richardson, R, Timmer, A, Stewart, C, Granger, S, Woods, R, Silacci, M, Grabulovski, D, & Newman, R (2018) A bispecific antibody that targets IL-6 receptor and IL-17A for the potential therapy of patients with autoimmune and inflammatory diseases. Journal of Biological Chemistry 293(24), 9326-9334.

Kumar, A,  Dhar, S, Campanelli, G,  Butt, NA Schallheim, JM, Gomez, CR, &  Levenson, AS (2018) MTA1 drives malignant progression and bone metastasis in prostate cancer. Molecular Oncology 12(9), 1596-1607.

Proia, DA, Smith, DL, Zhang, J, Jimenez, J-P, Sang, J, Ogawa, LS, Sequeira, M, Acquaviva, J, He, S, Zhang, C, Khazak, V, Astsaturov, I, Inoue, T, Tatsuta, N, Osman, S, Bates, RC, Chimmanamada, C, & Ying, W (2015) HSP90 Inhibitor–SN-38 Conjugate Strategy for Targeted Delivery of Topoisomerase I Inhibitor to Tumors. Molecular Cancer Therapeutics 14(11), 2422-2432.

Raouf, S, Weston, C, Yucel, N, & Reproducibility Project: Cancer Biology (2015) Registered report: Senescence surveillance of pre-malignant hepatocytes limits liver cancer development. eLife e04105. DOI: 10.7554/eLife.04105.

Schommer, NN, Nguyen, J, Yung, BS, Schultheis, K, Muthumani, K, Weiner, DB, Humeau, L, Broderick, KE, & Smith TRF (2019) Active Immunoprophylaxis and Vaccine Augmentations Mediated by a Novel Plasmid DNA Formulation. Human Gene Therapy 30(4) 523-533.

Shields, BD, Koss, B, Taylor, EM, Storey, AJ, West, KL, Byrum, SD, Mackintosh, SG, Edmondson, R, Mahmoud, F, Shalin, SC, & Tackett, AJ (2019) Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma. Cancer Research 79(6), 1113-1123.

Verco, J, Johnston, W, Frost, M, Baltezor, M, Kuehl, PJ, Lopez, A, Gigliotti, A, Belinsky, SA, Wolff, R, & diZerega, G (2019) Inhaled Submicron Particle Paclitaxel (NanoPac) Induces Tumor Regression and Immune Cell Infiltration in an Orthotopic Athymic Nude Rat Model of Non-Small Cell Lung Cancer. Journal of Aerosol Medicine and Pulmonary Drug Delivery 32(5), 266-277.

Wallace EM, Rizzi, JP, Han, G,  Wehn, PM, Cao, Z Du, X, Cheng, T,  Czerwinski, RM, Dixon, DD, Goggin, BS,  Grina, JA, Halfmann, MM, Maddie, MA, Olive, SR, Schlachter, ST, Tan, H, Wang, B, Wang, K, Xie, S,  Xu, R, Yang, H & Josey, JA (2016) A Small-Molecule Antagonist of HIF2a Is Efficacious in Preclinical Models of Renal Cell Carcinoma. Cancer Research 76(18), 5491-5500.

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