COVID-19: New Histopathology Capabilities for Research

Collaboration within the scientific community is essential for rapid progress. Our highly skilled team is ready to accelerate your COVID-19 research.  In this time of uncertainty one thing is clear – accurate data matters.

Quantitative In Situ Hybridization

Comprehensive services include ISH stainingwhole slide imaging, and quantitative analysis. New SARS-CoV-2-specific mRNA probes:

  • V-nCoV2019-S. This probe targets the S gene encoding the spike protein. This probe has been designed to be specific for SARS-CoV-2 and will not detect other coronaviruses.
  • V-nCoV2019-S-sense. This “sense” probe targets the antisense strand of the S gene, which can be used to visualize viral replication in individual cells.
  • Hs-ACE2. ACE2 is the cellular receptor for SARS-CoV-2. This probe will provide highly sensitive detection of ACE2 expression in cells and tissue sections, information critical to understand the tropism and pathogenesis of this novel virus.
  • Hs-TMPRSS2. TMPRSS2 is a cellular serine protease and primes the spike protein (S) for cellular entry.

Immunuhistochemistry and Immunofluorescence

Optimization and staining for novel and commercial antibodies against SARS-CoV-2. Commercial antibodies are available against the spike, envelope, and nucleocapsid proteins.

COVID-19 Tissue for Research

COVID-19 tissue is now available for research from our accredited tissue bank partners.

Pathology Review in the Cloud

Access a network of experienced Board-Certified Pathologists.

Please contact us to apply these methods to your research.

Image courtesy of: CDC/ Alissa Eckert, MS; Dan Higgins, MAMS

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