Resources

AI Powered Pathology and Spatial Genomics: a Precision Medicine Approach

Spatial genomics and digital pathology continue to evolve at a rapid pace, generating large amounts of data. There is a critical unmet need for advanced tools to expedite spatial data generation, visualization, and analysis to facilitate an improved understanding of health and disease, especially with the development of personalized cancer treatments. In this study we …

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Poster – Analysis of a NASH Mouse Model Using Artificial Intelligence

In a unique collaboration between multiple companies, Reveal has applied deep learning-based models to validate a diet-induced mouse NASH model that can be utilized in directed research studies for therapeutic drug development. Along with the white paper summarizing the mouse model validation, we prepared a poster to be presented at the Experimental Biology 2020 Annual …

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Validation of a NASH Mouse Model – White Paper

Validation of an Off-the-Shelf, Diet-Induced NASH Mouse Model using Digital Whole Slide Scanning of Liver Tissue and Artificial Intelligence-Enabled, Quantitative Histopathological Analysis Download the PDF White Paper Summary: Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are common chronic liver disorders resulting in lipid accumulation in the liver, inflammation, hepatocyte damage, and fibrotic scarring, …

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COVID-19: New Histopathology Capabilities for Research

Collaboration within the scientific community is essential for rapid progress. Our highly skilled team is ready to accelerate your COVID-19 research.  In this time of uncertainty one thing is clear – accurate data matters. Quantitative In Situ Hybridization Comprehensive services include ISH staining, whole slide imaging, and quantitative analysis. New SARS-CoV-2-specific mRNA probes: V-nCoV2019-S. This probe targets the S gene encoding the …

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NASH: IHC Digital Assays for Immune Cell Quantification

Research into developing effective treatments for non-alcoholic steatohepatitis (NASH) is becoming more important as the incidence of NASH increases in the general population. Mouse and rat models are used in the development of NASH therapeutics to help investigators better understand the pathophysiological mechanisms of the disease. Treatment strategies for NASH that target and modulate the …

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Deep Learning-Based Assessment and Sophisticated Quantification for Wound Healing and Skin Metrics

The staggering cost of healthcare in America continues to rise, especially for wound healing. In 2014, wound-related healthcare expenses for Medicare beneficiaries were conservatively estimated at $28.1 billion, with over 8 million patients reporting at least one type of wound or infection.1 Improved methods that analyze the complex stages of wound healing have potential to …

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Reveal Biosciences and QuantumCyte Partner to Offer a New Generation of Multi-omic Data

Precision medicine has come a long way towards benefiting patient outcomes and enhancing research tools. In recent years, the integration of multi-scale omics from genomic, proteomic, and transcriptomic foundations has impacted how biological pathways and disease progression are studied. The industry has rapidly progressed due to both improved, ultra-sensitive technologies and increased awareness across expert …

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imageDx: NASH – A New Generation of Quantitative NASH Data

Traditional NAFLD Activity Scoring Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent causes of liver dysfunction, with some estimates suggesting up to 30% of the general population as being affected (1). NAFLD, while mainly asymptomatic, can progress to non-alcoholic steatohepatitis (NASH) in a portion of individuals. NASH is characterized by multiple pathologic …

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Spheroids: Research in 3D

What Are Spheroids? A spheroid is a small, spherical cluster of cells that acts as a 3D cell culture. The term “organoid” is also used interchangeably with “spheroid”, although the former specifically refers to a 3D cluster of organ-specific cells. Spheroids and organoids can be artificially assembled through different methods, including the use of centrifugal …

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