imagedx:
NASH

Increase accuracy, reproducibility, and scale of NASH and fibrosis liver scoring.

the process

Tissue

Staining

Imaging

Analysis

Automated NAFLD SCORING


Co-developed with a Team of Leading US Pathologists

Data Input Options:  Whole slide images, fixed tissue or slides

Data Output:  Steatosis (micro- and macro-vesicular), Lobular Inflammation, Ballooning, Mallory Bodies, and Fibrosis

quantitative nafld activity scoring

AI-based models to identify and precisely quantify steatosis, lobular inflammation, and ballooning.  Data are reported as precise percentages or cells per unit area, and can be translated into the more traditional NAFLD Activity Score.

NAFLD ACTIVITY SCORE (0-8) = Steatosis (0-3) + Lobular Inflammation (0-3) + Hepatocellular Ballooning (0-2)

STEATOSIS

Data reported includes total steatosis plus micro- and macro-vesicular steatosis.

LOBULAR INFLAMMATION

Lobular inflammation including inflammatory cells per mm2.

BALLOONING

Hepatocellular ballooning reported as mild, medium or severe and also expressed as a percentage of cells per cm2.

quantitative fibrosis scoring

fibrosis

AI-based models to identify and quantify liver fibrosis including a precise percentage as well as the traditional fibrosis score.  Rodent and human models are available.  Quantitative fibrosis scores can be calculated from Masson’s Trichrome or Picrosirius Red stains.

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