imageDx PRism

AI-powered multiplex immunofluorescence data and CellCarta expertise for Akoya® & Ultivue®

imageDx PRISM from Reveal Biosciences applies advanced AI models to generate cell-by-cell data, spatial biomarker characterization, and predictive patient outcome data from multiplex immunofluroescence images.


Quantify: Quantitative cell-by-cell data
Explore: Microenvironment & spatial data analysis
Predict: AI pattern discovery & predictive models


Quantitative Cell-by-Cell Data

Quantitative Cell-by-Cell Multiplex Immunofluorescence Data

Quantitative cell-by-cell data reported across the entire image including percent positivity & colocalization.

Microenvironment & Spatial Data Analysis

Spatial Data Analysis for Multiplex Immunofluorescence

Multi-cell microenvironment & spatial data analysis includes cluster analysis, proximity data for predefined markers, and distance to tumor-stroma interface.

AI Pattern Discovery & Predictive Models

AI Pattern Discovery for Multiplex Immunofluorescence Data

Custom AI models developed using graph neural networks to interrogate pattern formation and/or predict patient outcomes.

CellCarta Multiplex Panels with imageDx PRISM Analysis

Akoya & Ultivue Multiplex immunofluorescence is performed at the CellCarta specialized CAP/CLIA laboratory at Lake Forest, CA (formerly Mosaic Laboratories)

Akoya Opal® Chemistry

Immune Profile Panel – CD8+CD68+CD3+ PanCK+Open Position

Immuno-Contexture Panel – CD8+CD68+PD-L1+FoxP3+ PanCK+Open Position

Exhaustion Panel – CD8+CD4+CD20+FoxP3+ PD-1+Open Position

Activated TIL Status Panel – CD8+CD3+Ki67+Grz B+ PanCK+Open Position

M1/M2 Polarisation Panel – CD8+CD68+PD-L1+ PD-1+CD168+Open Position

Custom Assay Development Available

Ultivue® multiplex Panels

Immuno8 panel – CD3+CD4+CD8+CD68+FoxP3+PD-1+PD-L1+CK/SOX10+Nuclear counterstain
Ultivue FixVUE, FlexVUE, and U-Vue Mutiplex Immunofluorescence

Akoya & Ultivue Multiplex Immunofluorescence Powered By:

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